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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HRH4 All Species: 0
Human Site: T242 Identified Species: 0
UniProt: Q9H3N8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.78
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3N8 NP_001137300.1 390 44496 T242 R R S L S A S T E V P A S F H
Chimpanzee Pan troglodytes Q9N2A7 440 48835 G228 N M P S S D D G L E H N K I Q
Rhesus Macaque Macaca mulatta P56489 460 51414 P252 Q P G A E G S P E T P P G R C
Dog Lupus familis XP_547634 395 45119 K248 R T S L S E Q K E T A P S V P
Cat Felis silvestris
Mouse Mus musculus Q91ZY2 391 44230 K244 R T S N P G L K E S A A S R H
Rat Rattus norvegicus Q91ZY1 391 44005 K244 R T S L P G L K E P A A S L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520508 432 48627 R267 R S S L L V W R Q R T L D S D
Chicken Gallus gallus P49578 639 71958 K355 T K R S S R R K Y R R C H F W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001020689 473 53488 R297 V R P V E E S R V A D L A S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18775 517 58629 R297 F H A R E S T R L L L K Q V S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.2 25.8 71.9 N.A. 68.5 69.5 N.A. 41.4 23.3 N.A. 35.3 N.A. N.A. N.A. 24.7 N.A.
Protein Similarity: 100 48.8 45.8 81 N.A. 78.5 79.5 N.A. 55 38.1 N.A. 51.5 N.A. N.A. N.A. 42.3 N.A.
P-Site Identity: 100 6.6 20 40 N.A. 40 46.6 N.A. 20 13.3 N.A. 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 6.6 26.6 40 N.A. 40 46.6 N.A. 26.6 20 N.A. 26.6 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 10 0 0 0 10 30 30 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % C
% Asp: 0 0 0 0 0 10 10 0 0 0 10 0 10 0 10 % D
% Glu: 0 0 0 0 30 20 0 0 50 10 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % F
% Gly: 0 0 10 0 0 30 0 10 0 0 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 30 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 10 0 0 0 0 0 40 0 0 0 10 10 0 0 % K
% Leu: 0 0 0 40 10 0 20 0 20 10 10 20 0 10 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 20 0 20 0 0 10 0 10 20 20 0 0 10 % P
% Gln: 10 0 0 0 0 0 10 0 10 0 0 0 10 0 10 % Q
% Arg: 50 20 10 10 0 10 10 30 0 20 10 0 0 20 10 % R
% Ser: 0 10 50 20 40 10 30 0 0 10 0 0 40 20 10 % S
% Thr: 10 30 0 0 0 0 10 10 0 20 10 0 0 0 0 % T
% Val: 10 0 0 10 0 10 0 0 10 10 0 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _